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Prostaglandins in Human Seminal Fluid and Its Relation to Fertility

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Prostaglandins, Leukotrienes, and Lipoxins

Abstract

Human seminal fluid contains a number of prostaglandins (PGs) in large amounts. The first identified compounds were PGE1, PGE2, PGE3, PGF1, and PGF (Samuelsson, 1963). More recently, 19-hydroxy-PGE1, 19-hydroxy-PGE2, 19-hy-droxy-PGF, and 19-hydroxy-PGF have been identified. The 8ß-isomers of these compounds are also present (Taylor, 1979; Taylor and Kelly, 1974, 1975). Although 50 years have now elapsed since von Euler (1936) first identified a new type of compound in human semen, which he named prostaglandin, the physio-logical function of the PGs in semen is still far from clarified. In this chapter, different possibilities that we have started to evaluate during the last years are discussed.

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Bygdeman, M., Bendvold, E., Gottlieb, C., Svanborg, K., Eneroth, P. (1985). Prostaglandins in Human Seminal Fluid and Its Relation to Fertility. In: Bailey, J.M. (eds) Prostaglandins, Leukotrienes, and Lipoxins. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4946-4_41

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  • DOI: https://doi.org/10.1007/978-1-4684-4946-4_41

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4948-8

  • Online ISBN: 978-1-4684-4946-4

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